Organic Chemistry

For students from Department of Medicine

Prerequisite course: General Chemistry

Teaching assistant: Yun-Chin Yang(楊雲欽, 3366-4087)

Syllabus:

1. Introduction

Bondings, acids and bases

2. Alkanes

Conformational analysis of alkanes, radical halogenation and other related chemistry

3. Stereochemistry

Optical isomerism, Cahn-Ingold-Prelog rule and absolute configuration, conformation analysis of cyclic alkanes

4. Haloalkanes

Displacement reactions, elimination reactions, chemistry of carbanions

5. Alcohols and Ethers

Preparation, reactions (displacement, dehydration, oxidation)

6. Alkenes

Preparation, reactions (addition reactions, cycloaddition, oxidative cleavage reactions)

7. Alkynes

Preparation, reactions (deprotonation, selective reduction)

8. Aromatic Compounds

Aromaticity, reactions (electrophilic substitution, substituent effects, reactions at side chain(s)

9. Spectrophotometric Methods

Nuclear magnetic resonance, mass spectrometry, infrared spectrometry, UV-Vis spectrometry

10. Carbonyl Compounds

Preparation, reactions (acidity, oxidation and reduction, nucleophilic addition, Aldol condensation, Michael addition, Robinson annulation)

11. Carboxylic Acids and Derivatives

Preparation, reaction (acidity, esterification, hydrolysis of esters, ester condensation)

12. Amines

Basicity, preparation, reactions (acids and bases, formation of amide, diazonium ions)

13. Chemistry of Biological Molecules

Carbohydrates, amino acids and peptides, nucleic acids